Target (protein/gene name): FK506-binding protein (FKBP)-type peptidyl-propyl isomerase NCBI Gene # or RefSeq#:811507 Protein ID (NP or XP #) or Wolbachia#: XP_001350859.1 Organism: Plasmodium falciparum 3D7 Etiologic Risk Group (see link below): Background/Disease Information: Essentiality of this protein: Complex of enzymes: EC#: 5.2.1.8 Link to BRENDA EC# page: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=5.2.1.8 Enzyme Assay information (spectrophotometric, coupled assay ?, reagents): http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Enzyme_Assay/fkbindingprtn.Par.0001.File.tmp/fkbindingprtn.pdf http://www.brenda-enzymes.info/literature/lit.php4?e=5.2.1.8&r=2534 Structure Available (PDB or Homology model) -- PDB # or closest PDB entry if using homology model: -- Query Coverage (if not direct match): -- Max Ident (if not direct match): Druggable Target (see Databases for this): Current Inhibitors: Expression Information (has it been expressed in bacterial cells): Purification Method: Image of protein (PyMol or etc): Amino Acid Sequence:
length of your protein in Amino Acids 304 aa Molecular Weight of your protein in kiloDaltons using the Expasy ProtParam website Molar Extinction coefficient of your protein at 280 nm wavelength: CDS Gene Sequence:
NCBI Gene # or RefSeq#: 811507
Protein ID (NP or XP #) or Wolbachia#: XP_001350859.1
Organism: Plasmodium falciparum 3D7
Etiologic Risk Group (see link below):
Background/Disease Information:
Essentiality of this protein:
Complex of enzymes:
EC#: 5.2.1.8
Link to BRENDA EC# page:
http://www.brenda-enzymes.org/php/result_flat.php4?ecno=5.2.1.8
Enzyme Assay information (spectrophotometric, coupled assay ?, reagents):
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Enzyme_Assay/fkbindingprtn.Par.0001.File.tmp/fkbindingprtn.pdf
http://www.brenda-enzymes.info/literature/lit.php4?e=5.2.1.8&r=2534
Structure Available (PDB or Homology model)
-- PDB # or closest PDB entry if using homology model:
-- Query Coverage (if not direct match):
-- Max Ident (if not direct match):
Druggable Target (see Databases for this):
Current Inhibitors:
Expression Information (has it been expressed in bacterial cells):
Purification Method:
Image of protein (PyMol or etc):
Amino Acid Sequence:
length of your protein in Amino Acids 304 aa
Molecular Weight of your protein in kiloDaltons using the Expasy ProtParam website
Molar Extinction coefficient of your protein at 280 nm wavelength:
CDS Gene Sequence:
GC% Content for gene:
CDS Gene Sequence (codon optimized) - after having done Primer Design:
GC% Content for gene (codon optimized):
Primer design results for pNIC-Bsa4 cloning (list seqeunces of all of your ~40 nt long primers):
Primer design results for 'tail' primers (this is just 2 sequences):